Amanda Ramer-Tait

Teaching and/or Extension Activities:

  • Advanced Topics in Immunology (VBMS 910)
  • Functional Foods and Nutraceuticals (FDST 470/870)

Research Area:

Research interests in the Ramer-Tait laboratory are focused on understanding host-microbiota interactions. In particular, our research program aims to: (1) determine the causative relationships between the gut microbiota and chronic, inflammatory diseases, (2) understand how dietary interventions, including dietary fibers, can be used to improve inflammatory diseases via modulation of the gut microbiota, and (3) develop new approaches to disease prevention and treatment that include microbiome manipulation.

Selected Publications:

  1. Li X, Leonardi I, Semon A, Doron I, Gao IH, Putzel GG, Kim Y, Kabata H, Artis D, Fiers WD, Ramer-Tait AE, Iliev ID. Response to fungal dysbiosis by gut-resident CX3CR1+ mononuclear phagocytes aggravates allergic airway disease. 2018. Cell Host Microbe. 24:1-10.
  2. Kittana H, Gomes-Neto JC, Sanderfer K, Geis AL, Segura Muñoz RR, Cody LA, Schmaltz RJ, Bindels LB, Sinha R, Hostetter JM, Benson AK, Ramer-Tait AE. Commensal Escherichia coli strains can promote intestinal inflammation via differential interleukin-6 production. 2018. Front Immunol. 9:2318.
  3. Martínez I, Maldonado-Gomez XM, Gomes-Neto JC, Kittana H, Ding H, Schmaltz R, Joglekar P, Cardona RJ, Marsteller NL, Kembel SW, Benson AK, Peterson DA, Ramer-Tait AE, Walter J. Experimental evaluation of the importance of colonization history in early-life gut microbiota assembly. 2018. eLIFE. 7. pii:e36521.
  4. Lin XB#, Wang T#, Stothard P, Corander J, Wang J, Baines J, Knowles SCL, Baltrūnaitė L, Tasseva G, Schmaltz R, Tollenaar S, Cody LA, Grenier T, Wu W, Ramer-Tait AE, Walter J. Ecological facilitation among members of multi-species biofilms in the mouse gastrointestinal tract. 2018. ISME J. 12:2770-2784. #represents equal contribution.
  5. Kittana H, Quintero-Villegas MI, Bindels LB, Gomes-Neto JC, Schmaltz RJ, Segura Munoz RR, Cody EA, Moxley R, Hostetter J, Hutkins RW, Ramer-Tait AE. Galactooligosaccharide supplementation provides protection against Citrobacter rodentium-induced colitis without limiting pathogen burden. 2018. Microbiology. 164:154-162.
  6. Gomes-Neto JC, Kittana H, Mantz S, Segura Munoz RR, Schmaltz RJ, Bindels LB, Clarke J, Hostetter JM, Benson AK, Walter J, Ramer-Tait AE. A gut pathobiont synergizes with the microbiota to instigate inflammatory disease marked by immunoreactivity against other symbionts but not itself. 2017. Sci Rep. 7:17707.
  7. Clavel T, Gomes Neto JC, Lagkouvardos I, Ramer-Tait AE. Deciphering interactions between the gut microbiota and the immune system via microbial cultivation and minimal microbiomes. 2017. Immunol Rev. 279:8-22.
  8. Perez-Munoz ME, Arrieta MC, Ramer-Tait A, Walter J. A critical assessment of the 'sterile womb' and 'in utero colonization' hypotheses: implications for research on the pioneer infant microbiome. 2017. Microbiome. 5:48.
  9. Gomes-Neto JC, Mantz S, Held K, Sinha R, Benson AK, Walter J, Ramer-Tait AE. A real-time PCR assay for accurate quantification of the individual members of the Altered Schaedler Flora microbiota in gnotobiotic mice. 2017. J Microbiol Methods. 135:52-62.
  10. Bindels LB, Segura Munoz RR, Gomes Neto JC, Mutemberezi V, Martínez I, Salazar N, Cody EA, Quintero-Villegas MI, Kittana H, de los Reyes-Gavilán CG, Schmaltz RJ, Muccioli GG, Walter J, Ramer-Tait AE. Resistant starch can improve insulin sensitivity independently of the gut microbiota. 2017. Microbiome. 5:12.
  11. Yang J, Bindels LB, Munoz RS, Martinez I, Walter J, Ramer-Tait AE*, Rose DJ*. Disparate metabolic responses in mice fed a high-fat diet supplemented with maize derived non-digestible feruloylated oligo- and polysaccharides are linked to changes in the gut microbiota. 2016. PLoS One. 11:e0146144. *represents equal contribution.
  12. Druart C#, Bindels LB#, Schmaltz R, Neyrinck AM, Cani PD, Walter J, Ramer-Tait AE*, Delzenne NM*. Ability of the gut microbiota to produce PUFA-derived bacterial metabolites: proof of concept in germ-free versus conventionalized mice. 2015. Mol Nutr Food Res. 59(8):1603-13. # *represent equal contributions

Find a complete list of Dr. Ramer-Tait’s publications in PubMed or GoogleScholar

Amanda Ramer-Tait
Associate Professor

Education:

B.S., Biochemistry, Western Kentucky University

Ph.D., Immunobiology, Iowa State University

Post Doc,
Immunology, Microbiology and Parasitology, Iowa State University

Contact Information:

260 Food Innovation Center
Lincoln, NE 68588-6205
402 472 7293
aramer-tait2@unl.edu

Nebraska Food for Health Center