My long-term research objective is to characterize natural bioactive agents and their interactions with various types of food matrices through the integration of metabolomic and physiochemical approaches. This information is then used as a means (1.) to facilitate the development of functional foods and/or nutraceuticals and (2.) to study the health promoting and/or toxic properties of these systems at the cellular level.
Five Selected Publications:
Christiansen, C. L., C. W. Weller, V. L. Schlegel., S. L. Cuppett, T. P. Carr. 2007. Extraction and characterization of lipids from the kernels, leaves and stalks of nine grain sorghum parent lines. Cereal Chem. 84(5):463-470. Biotechnol.
Schlegel, V. L., A. Yong., S.-Y. Foo, (2007). Development of a direct sampling method for verifying the cleanliness of equipment shared with peanut products. Food Control 18(12):1494-1500
Plantz, B.A., J. Sinha, L. Villarete, K. Nickerson, V.L. Schlegel. 2006. Pichia pastoris fermentation process optimization: Energy state and testing a growth associated model. Appl. Microbiol. Biotechnol. 72:297-305.
Wijeratne, S.K., S.L. Cuppett, S.L, V. Schlegel, 2005. Hydrogen peroxide induced oxidative stress damages and antioxidant enzyme response in Caco-2 human colon cells. J. Agric. Food Chem. 53:8768.
Carr, T.P., C.W. Weller, V. Schlegel, S. Cuppett, D.M. Guderian, and K.R. Johnson. 2005. Grain sorghum lipid extract reduces cholesterol absorption and plasma non-HDL cholesterol concentration in hamsters.
